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The CINDERELLA project intends to test and validate the implementation of an AI-based tool for a safer and evidence-based clinical decision for patients proposed for locoregional treatment, making it easily applied in clinical practice anywhere in the world. A better prediction of aesthetic outcomes of the different breast surgical approaches can improve patient satisfaction and quality of life, reduce anxiety and depression levels, as well as potential revisional surgeries.

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Can we understand AI without using explainable AI tools?
At the CINDERELLA Workshop, Helena Montenegro presented a thought-provoking talk on the CINDERELLA use case—showing how interpretability can still be achieved.

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https://www.youtube.com/watch?v=vxJ6dhgdOzc&t=12s

@TanjaSpanic Fantastic talk by my @Cinderella_EU colleague @andrepfob at #ESMOBreast25!

How can AI help identify patients with pCR?

False-negative rate for intelligent vacuum-assisted biopsy in the breast is close to 0% - impressive! 🤖🧠🔬💪

Can AI explain itself… in words?

At the CINDERELLA Workshop, Isabel Rio-Torto explored how natural language explanations can help bridge the gap between deep learning models and human understanding in medical imaging.

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https://www.youtube.com/watch?v=RbtfnpGazV4&t=3s

We made it!

The CINDERELLA clinical trial has officially closed patient recruitment with 1,000 participants enrolled – reaching 100% of our goal!

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Wilson Silva explored how example- and concept-based explanations can make medical AI more trustworthy and understandable. From cancer research to AI generalizability and privacy, his work is reshaping how we explain complex models.

Click here ⬇️
https://youtu.be/8ZGaFrPQk9w?si=5HP4InzSxlem_z-S

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background

I was devastated when I saw the result of the surgery of one of my best friends. I always thought I was very lucky because I managed to kept my breast and quite frankly, I thought my breasts look great after the operation. But then I looked at my friend and I almost cried. If she didn’t told me, I would never had guessed which breast has been the one submitted to surgery.
Now when I look at me, I know that the result is not what I thought and I wish I had the opportunity to knew it before

Ana Paula Ferreira

2.3M
Breast Cancer
World Wide Incidence
90%
Locoregional Treatment
± 2M Submitted
60%
Breast Conserving Treatment
± 1,2M Surgery and Radiotherapy
40%
Mastectomy
± 800K Surgery with or without Reconstruction With or without Radiotherapy
Partners

This project has received funding from the European Union's Horizon Europe research and innovation programme under Grant Agreement number 101057389